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Background: Early detection of colorectal adenoma plays crucial roles in CRC early prevention and intervention. Current detection by colonoscopy is not suitable for mass screening due to its high costs and low compliance. The SEPT9 gene methylation assay is a new qPCR-based assay for CRC screening, and was found to be effective for adenoma detection. However, its ability in detecting adenoma has not been fully examined.
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Song et al. (2018) studied this question.
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