Why the study?
Does 2-D echocardiography improve the accuracy of left ventricular mass estimation compared to M-mode echocardiography in mice?
Population
25 anesthetized FVB/N mice (Mus musculus)
Comparison
Two-dimensional echocardiography using… vs M-mode echocardiography and gravimetric LV weight
Design
Preclinical
Authors
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Supports 2-D LV mass assessment in mice; leaves open translation to human echocardiography.
Does 2-D echocardiography improve the accuracy of left ventricular mass estimation compared to M-mode echocardiography in mice?
The 2-D area-length method provides an accurate alternative to M-mode echocardiography for in vivo measurement of left ventricular mass in mice with symmetrical ventricles.
Kiatchoosakun et al. (2002) studied this question.
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