Why the study?
What are the haemodynamic effects of induction of anaesthesia with ICI 35 868 in patients with severe aortic or mitral valve disease?
Population
10 patients with severe aortic or mitral valve disease
Design
Case_series
Follow-up
at induction of anaesthesia
Authors
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Caution with ICI 35 868 induction in severe valvular disease; Level 5 data leaves open need for controlled trials.
What are the haemodynamic effects of induction of anaesthesia with ICI 35 868 in patients with severe aortic or mitral valve disease?
Induction of anaesthesia with ICI 35 868 in patients with severe valvular heart disease causes significant decreases in mean arterial pressure and heart rate without major changes in cardiac index.
Aun et al. (1984) studied this question.
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