What question did this study set out to answer?

To develop an inexpensive, portable microcomputer software package capable of handling primary DNA and RNA sequence analyses typically restricted to large time-sharing systems.

January 1, 1982Nucleic Acids ResearchOpen Access

Portable microcomputer software for nucleotide sequence analysis

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Authors

BFBrian FristenskyUniversity of Manitoba JLJohn T. LisNational Institute of Genetics RWRay WuPurdue University West Lafayette

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Implication

Software report demonstrates comprehensive nucleotide sequence analysis on microcomputers, highlighting accessible and low-cost genetic data processing across diverse hardware platforms.

Key Points

To develop an inexpensive, portable microcomputer software package capable of handling primary DNA and RNA sequence analyses typically restricted to large time-sharing systems.
Wrote software programs in Standard Pascal on an Apple II microcomputer to optimize portability across micro-, mini-, and mainframe systems.
Programmed integrated functional modules for sequence numbering, translation, restriction enzyme site identification, homology searching, and nucleotide distribution profiling.
Implemented comprehensive sequence handling tools on microcomputers, including graphical data displays and dot-matrix homology plots.
Overcame microcomputer hardware constraints to perform nucleotide sequence data manipulation at a fraction of the cost of mainframe computing systems.

Cite This Study

Fristensky et al. (1982) studied this question.

synapsesocial.com/papers/6a7f386d363dc28cab6f36d4 https://doi.org/10.1093/nar/10.20.6451

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Implication

Software report demonstrates comprehensive nucleotide sequence analysis on microcomputers, highlighting accessible and low-cost genetic data processing across diverse hardware platforms.

Portable microcomputer software for nucleotide sequence analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Portable microcomputer software for nucleotide sequence analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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