Why the study?
Does perioperative epidural blockade improve the anticatabolic effects of glucose after colorectal surgery?
Population
16 patients after colorectal surgery
Comparison
Perioperative epidural blockade with local… vs No perioperative epidural blockade
Design
RCT, randomly assigned
Follow-up
second postoperative day (6-h study)
Authors
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Epidural blockade enables glucose to reduce protein oxidation after colorectal surgery; extends metabolic RCT evidence supporting combined use.
Does perioperative epidural blockade improve the anticatabolic effects of glucose after colorectal surgery?
Epidural blockade facilitates whole body glucose uptake and inhibits endogenous protein oxidation after abdominal surgery, shifting substrate utilization from protein to glucose.
Schricker et al. (2000) studied this question.
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