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December 1, 1980Acta Anaesthesiologica Scandinavica

Effect of Epidural Analgesia on Glucose Tolerance During Surgery

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Why the study?

Does epidural lumbar blockade prevent impaired glucose tolerance during surgery in surgical patients compared to general anesthesia?

Population

12 surgical patients

Comparison

Epidural lumbar blockade (Th8-S5) vs General anesthesia with enflurane

Design

Cohort

Follow-up

during surgery

Authors

CJCyrus JensenLeeds General InfirmaryPBP. G. BerthelsenUniversity of CopenhagenCKChristiane KühlUniversitätsklinikum Aachen

Discussion

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Implication

May support epidural anesthesia to preserve intraoperative glucose tolerance; hypothesis-generating and requires randomized confirmation before practice change.

Structured PICO

Does epidural lumbar blockade prevent impaired glucose tolerance during surgery in surgical patients compared to general anesthesia?

P
Population
12 surgical patients
I
Intervention
Epidural lumbar blockade (Th8-S5)
C
Comparator
General anesthesia with enflurane
O
Outcome
Plasma glucose concentration after intraoperative glucose loadsurrogate

Epidural analgesia preserves normal glucose tolerance during surgery compared to general anesthesia with enflurane.

Cite This Study

Jensen et al. (1980) studied this question.

synapsesocial.com/papers/6a82adbcfb68d755121c2285https://doi.org/10.1111/j.1399-6576.1980.tb01586.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of Epidural Analgesia on the Catecholamine and Cyclic AMP Responses to Surgery1980 · 98 citations
  2. 2CORTISOL BINDING CAPACITY IN PLASMA DURING ANAESTHESIA AND SURGERY1974 · 59 citations
  3. 3Glucose Tolerance and Insulin Response during and after Elective Skeletal Surgery1974 · 34 citations
  4. 4Glucose utilization and insulin secretion during surgery in man1974 · 83 citations
  5. 5C‐PEPTIDE AND INSULIN DURING BLOCKADE OF THE HYPERGLYCAEMIC RESPONSE TO SURGERY BY EPIDURAL ANALGESIA1977 · 20 citations