Why the study?
Does general anesthesia with epidural block with bupivacaine alter glucose and protein kinetics in patients undergoing colorectal surgery receiving i.v. glucose?
Population
16 patients undergoing colorectal surgery receiving i.v. glucose at 2 mg x kg(-1) x min(-1)
Comparison
General anesthesia with epidural block with… vs General anesthesia alone
Design
Other
Follow-up
2 h after the operation
Authors
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Epidural block may blunt perioperative hyperglycemia; hypothesis-generating for outcomes and protein effects, needing RCTs.
Does general anesthesia with epidural block with bupivacaine alter glucose and protein kinetics in patients undergoing colorectal surgery receiving i.v. glucose?
Epidural block attenuates the perioperative increase in plasma glucose and suppresses endogenous glucose production but does not exert a protein-sparing effect during the acute phase of surgical stress.
Lattermann et al. (2003) studied this question.
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