Why the study?
Coronary CT angiography PCAT markers are promising indicators of inflammation, but the effect of patient and imaging parameters on associations between non-calcified plaque and PCAT attenuation and gradient needed evaluation.
Does the association between non-calcified plaque and PCAT markers persist after adjusting for patient and imaging characteristics in patients with stable chest pain and zero calcium score?
Population
1652 consecutive patients with stable chest pain and zero calcium scores
Comparison
Association of plaque markers with PCAT attenuation and gradient unadjusted vs adjusted for patient and imaging characteristics
Design
Single-center retrospective analysis
Authors
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Unadjusted PCAT should not infer inflammation on zero-CAC CCTA; leaves open an independent NCP link after technical correction.
Does the association between non-calcified plaque and PCAT markers persist after adjusting for patient and imaging characteristics in patients with stable chest pain and zero calcium score?
Associations between non-calcified plaque and PCAT markers on CCTA do not persist after correcting for patient and imaging characteristics, highlighting the need to account for these factors in PCAT analysis.
Boussoussou et al. (2022) studied this question.
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