Population
100 consecutive patients admitted to a short-term medical ward
Design
Cross-sectional
Authors
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Clinicians should not rely on isolated CPK elevation alone to diagnose myocardial necrosis; cross-sectional data leaves open extracardiac sources in inpatients.
Isolated elevation of serum CPK activity is common in hospitalized patients and should not be used as the sole basis for diagnosing myocardial necrosis due to potential extracardiac causes.
M. A. Nevins (1973) studied this question.
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