Key result
Serum CPK isoenzyme analysis distinguished acute myocardial infarction, which consistently produced two isoenzymes, from surgery or intramuscular injections, which produced only one.
Why the study?
Does isoenzyme analysis distinguish CPK elevations after acute myocardial infarction from those after surgery or intramuscular injections in experimental animals and patients?
Does isoenzyme analysis distinguish CPK elevations after acute myocardial infarction from those after surgery or intramuscular injections in experimental animals and patients?
CPK isoenzyme analysis can distinguish myocardial infarction from surgery or intramuscular injections based on the presence of two isoenzymes versus one.
May distinguish MI from procedural CPK rises in select cases; leaves open prospective validation before wider adoption.
Serum creatine phosphokinase (CPK) elevations after surgery and intramuscular injections were distinguished from those occurring after acute myocardial infarction by isoenzyme analysis with a new sensitive technique. Two CPK isoenzymes were consistently seen after myocardial infarction in experimental animals and patients, while only one was seen after intramuscular injections or surgery.
No takes yet. Share an insight, caveat, or question.
Klein et al. (1973) studied this question. Serum CPK isoenzyme analysis distinguished acute myocardial infarction, which consistently produced two isoenzymes, from surgery or intramuscular injections, which produced only one.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: