Why the study?
Does the determination of CPK isoenzymes (MB-CPK) accurately identify acute myocardial infarction and correlate with the clinical course?
Population
700 patients, including 400 with definite acute myocardial infarction and 300 with increased CPK levels due…
Design
Cohort
Authors
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Supports MB-CPK for AMI diagnosis in this cohort; leaves open validation against modern troponin standards.
Does the determination of CPK isoenzymes (MB-CPK) accurately identify acute myocardial infarction and correlate with the clinical course?
MB-CPK is a highly sensitive and specific biomarker for acute myocardial infarction, and its temporal patterns correlate with the patient's clinical course.
Neufeld et al. (1977) studied this question.
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