Additive effects of age and silent myocardial ischemia on the left ventricular response to upright cycle exercise

45 men, comprising 8 clinically healthy older men (76 +/- 3 yr) with silent myocardial ischemia (ischemic ECG and Tl scan responses to prior exercise), 16 age-matched older men with normal responses (old controls), and 21 healthy young men (33 +/- 1 yr).

Maximal upright cycle ergometry

Age-matched older controls and young controls

Left ventricular response to exercise, including left ventricular ejection fraction, end-diastolic volume index, and end-systolic volume index at rest and peak effortsurrogate