Isolation of Porcine Immunoglobulins and Determination of the Immunoglobulin Classes of Transmissible Gastroenteritis Viral Antibodies
Population
Sows experimentally or naturally infected with live virulent transmissible gastroenteritis virus, and sows…
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Route of exposure shapes antibody isotype in sow colostrum and milk; leaves open optimal TGE vaccination strategies for neonatal protection.
Structured PICO
P
Population
Sows experimentally (orally) or naturally infected with live virulent transmissible gastroenteritis (TGE) virus, and sows vaccinated intramuscularly or intramammarily with live attenuated TGE virus
I
Intervention
Oral/natural infection with live virulent TGE virus or intramuscular/intramammary vaccination with live attenuated TGE virus
O
Outcome
Immunoglobulin classes (IgA, IgG, IgM) of neutralizing antibodies to transmissible gastroenteritis (TGE) virus in serum, colostrum, and milksurrogate
The route of infection or vaccination markedly influences the immunoglobulin class of antibodies in colostrum and milk, with IgA being predominant after oral/natural infection.
Cite This Study
Saif et al. (1972) studied this question.