Why the study?
Do elevated coagulation markers at day 2 and 7 predict death or new AMI within 90 days in patients with acute anterior myocardial infarction?
Population
314 consecutive patients with acute anterior myocardial infarction randomized in the FRAMI trial
Comparison
Measurement of coagulation markers at 2 and 7… vs Patients without serious clinical events
Design
Cohort, Patients were randomized to low molecular weight heparin or placebo in…
Follow-up
90 days
Authors
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May aid early risk stratification after anterior MI; hypothesis-generating and should not yet change practice.
Do elevated coagulation markers at day 2 and 7 predict death or new AMI within 90 days in patients with acute anterior myocardial infarction?
Elevated coagulation activation markers (fibrin monomer antigen and D-Dimer) early after anterior myocardial infarction predict an increased risk of adverse clinical outcomes at 90 days.
Kontny et al. (1999) studied this question.
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