Why the study?
Does ambulatory blood pressure monitoring improve the detection of the relationship between angiotensinogen gene polymorphism and hypertension compared to office measurements in untreated hypertensive subjects?
Population
50 untreated subjects referred for evaluation of office BP >140/90 mm Hg on at least two separate occasions
Comparison
Ambulatory blood pressure monitoring vs Office blood pressure measurements
Design
Cross-sectional
Authors
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ABPM may enhance detection of genetic BP associations over office readings; leaves open whether it should alter clinical hypertension assessment.
Does ambulatory blood pressure monitoring improve the detection of the relationship between angiotensinogen gene polymorphism and hypertension compared to office measurements in untreated hypertensive subjects?
Ambulatory blood pressure monitoring provides greater analytic power than office measurements for detecting genetic associations with hypertension.
Ali G. Gharavi (1997) studied this question.
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