Why the study?
Does diet and drug therapy reduce cardiovascular risk in patients with mild hypertension?
Population
692 men and women ages 21 to 65 years with mild hypertension and weight between 110% and 160% of ideal weight.
Comparison
Dietary interventions and drug therapy in… vs Usual diet and placebo drug combinations.
Design
RCT, Stratified by clinical center and race.
Follow-up
6 months
Authors
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Modest short-term CV risk reduction with weight loss plus atenolol in mild hypertension; extends support for dietary therapy as adjunct to pharmacotherapy.
Does diet and drug therapy reduce cardiovascular risk in patients with mild hypertension?
Dietary therapy, particularly weight reduction, is an important adjunctive treatment to pharmacotherapy for reducing overall cardiovascular risk in patients with mild hypertension.
Albert Oberman (1990) studied this question.
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