Why the study?
Does the Laguerre deconvolution technique applied to TR-LIFS data improve the in-vivo diagnosis of macrophage-rich atherosclerotic lesions in a rabbit model?
Population
Eight rabbits (73 areas) with normal and atherosclerotic aortas
Design
Preclinical
Authors
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May support macrophage detection in rabbit atherosclerosis models; leaves open human translation and clinical validation.
Does the Laguerre deconvolution technique applied to TR-LIFS data improve the in-vivo diagnosis of macrophage-rich atherosclerotic lesions in a rabbit model?
The Laguerre deconvolution technique applied to TR-LIFS data shows potential for in-vivo detection of macrophage infiltration in atherosclerotic lesions, a marker of plaque vulnerability.
Jo et al. (2006) studied this question.
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