Why the study?
Does valsartan improve medication compliance and persistence compared to amlodipine or lisinopril in patients initiating antihypertensive therapy?
Population
142,945 continuously benefit-eligible patients from a pharmacy benefit manager drug claims database who…
Comparison
Valsartan vs Amlodipine or lisinopril
Design
Cohort
Follow-up
12 months
Authors
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Valsartan was associated with higher persistence in this cohort; leaves open confirmation in randomized trials and effects on outcomes.
Does valsartan improve medication compliance and persistence compared to amlodipine or lisinopril in patients initiating antihypertensive therapy?
In a usual-care setting, patients initiating valsartan demonstrated significantly higher medication compliance and persistence at 12 months compared to those initiating amlodipine or lisinopril.
Wogen et al. (2003) studied this question.
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