Why the study?
Does artificial atrial fibrillation induced by right atrial stimulation produce the same ventricular rhythm as spontaneous atrial fibrillation in dogs?
Does artificial atrial fibrillation induced by right atrial stimulation produce the same ventricular rhythm as spontaneous atrial fibrillation in dogs?
Artificial atrial fibrillation in dogs does not accurately replicate the ventricular dysrhythmia seen in true atrial fibrillation, limiting its utility as an electrophysiological or hemodynamic model.
Limits utility of artificial AF models in dogs; leaves open need for validated spontaneous AF equivalents in arrhythmia research.
R-R interval sequences during artificial atrial fibrillation in dogs were studied in the same way as in patients in a previous study and compared with results obtained in dogs with spontaneous atrial fibrillation. Artificial atrial fibrillation was effected by right atrial stimulation in three closed-chest and one open-chest dog. The ventricular rhythm was studied by histograms and autocorrelograms. The ventricular dysrhythmia during artificial atrial fibrillation generally differed from that during true atrial fibrillation. Therefore the findings during artificial atrial fibrillation cannot be used without reservation to explain electrophysiological (or hemodynamic) phenomena in true atrial fibrillation.
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Strackee et al. (1971) studied this question.
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