Why the study?
Does insulin infusion improve myocardial blood flow in patients with type 2 diabetes and coronary artery disease?
Population
43 subjects with type 2 diabetes and coronary artery disease, mean age 63 +/- 7 years, mean HbA1c 7.1 +/…
Comparison
Insulin infusion during a euglycemic-hyperinsulin… vs Fasting state.
Design
Other
Authors
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Acute myocardial blood flow gains with insulin in diabetic CAD remain hypothesis-generating; outcome trials needed before practice consideration.
Does insulin infusion improve myocardial blood flow in patients with type 2 diabetes and coronary artery disease?
Insulin infusion acutely improves myocardial blood flow in both ischemic and nonischemic regions in patients with type 2 diabetes and CAD, suggesting a potential mechanism for its beneficial endothelial effects.
Läutamaki et al. (2006) studied this question.
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