Why the study?
Does intracoronary insulin infusion increase myocardial blood flow in men with coronary heart disease?
Population
10 fasting men (aged 51 to 68 years) with coronary heart disease.
Design
Other
Follow-up
60 minutes
Authors
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May reduce coronary tone in CHD without raising demand; leaves open clinical relevance pending larger trials.
Does intracoronary insulin infusion increase myocardial blood flow in men with coronary heart disease?
Physiologic elevation in local plasma insulin concentration increases coronary blood flow without increasing myocardial oxygen demand, suggesting a primary reduction in coronary tone.
McNulty et al. (2000) studied this question.
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