Why the study?
Does pleconaril improve clinical and virological outcomes in patients with potentially life-threatening enterovirus infections?
Population
38 patients with potentially life-threatening enterovirus infections treated on a compassionate-release basis
Design
Case_series
Authors
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May support compassionate pleconaril use in severe enterovirus; leaves open efficacy confirmation in randomized trials.
Does pleconaril improve clinical and virological outcomes in patients with potentially life-threatening enterovirus infections?
Pleconaril administered on a compassionate-use basis appears to be well-tolerated and associated with favorable clinical and virological responses in patients with life-threatening enterovirus infections.
Rotbart et al. (2001) studied this question.
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