Key result
Elevated preoperative BNP (>30 pg/ml, P<0.0001) or NT-proBNP (≥113 pg/ml, 8-fold increased risk) significantly predicted postoperative atrial fibrillation after major non-cardiac thoracic surgery.
Why the study?
Do preoperative plasma BNP or NT-proBNP levels predict the occurrence of postoperative atrial fibrillation in patients undergoing non-cardiac thoracic surgery?
Population
Patients undergoing non-cardiac thoracic surgery. 5 prospective observational studies were included as best…
Comparison
Preoperative plasma brain natriuretic peptide or… vs Lower or normal preoperative BNP/NT-proBNP levels
Design
Systematic_review
Follow-up
postoperative period
Authors
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Supports preoperative BNP/NT-proBNP testing for AF risk stratification after thoracic surgery; confirms predictive value in non-cardiac procedures.
Systematic Review
Do preoperative plasma BNP or NT-proBNP levels predict the occurrence of postoperative atrial fibrillation in patients undergoing non-cardiac thoracic surgery?
Effect estimate: 8-fold increased risk
p-value: p=<0.0001
Elevated preoperative BNP or NT-proBNP levels can effectively identify patients at high risk for developing postoperative atrial fibrillation after major non-cardiac thoracic surgery.
Toufektzian et al. (2015) conducted a systematic review in Non-cardiac thoracic surgery. Elevated preoperative BNP or NT-proBNP levels vs. Lower BNP or NT-proBNP levels was evaluated on Postoperative atrial fibrillation (8-fold increased risk, p=<0.0001). Elevated preoperative BNP (>30 pg/ml, P<0.0001) or NT-proBNP (≥113 pg/ml, 8-fold increased risk) significantly predicted postoperative atrial fibrillation after major non-cardiac thoracic surgery.
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