Why the study?
Does oral yohimbine increase blood pressure and sympathetic nervous outflow in unmedicated hypertensive patients?
Does oral yohimbine increase blood pressure and sympathetic nervous outflow in unmedicated hypertensive patients?
Oral yohimbine stimulates sympathetically mediated norepinephrine release, leading to a significant pressor response in unmedicated hypertensive patients.
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May warrant caution with yohimbine in hypertensives; hypothesis-generating for sympathetic effects on outcomes.
Grossman et al. (1993) studied this question.
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