Key result
A wearable carotid Doppler tracked stroke volume changes during simulated occlusion tests, showing strong correlation with stroke volume (r2=0.95) and 60% less VTI variability than duplex ultrasound.
Why the study?
The study was conducted to test the feasibility of a novel, wearable carotid Doppler ultrasound to track changes in cardiac output induced by end-inspiratory and end-expiratory occlusion tests.
Does a wearable carotid Doppler ultrasound accurately track changes in stroke volume induced by simulated end-inspiratory and end-expiratory occlusion tests in healthy subjects?
Observational (n=10)
Does a wearable carotid Doppler ultrasound accurately track changes in stroke volume induced by simulated end-inspiratory and end-expiratory occlusion tests in healthy subjects?
p-value: p=<0.0001
A wearable carotid Doppler patch can track stroke volume changes induced by respiratory occlusion tests with less variability than traditional duplex ultrasound.
Background and Aims To test the feasibility of a novel, wearable carotid Doppler ultrasound to track changes in cardiac output induced by end‐inspiratory and end‐expiratory occlusion tests. Methods We observed the pattern of Doppler change of the common carotid artery during a simulated end‐inspiratory and expiratory occlusion test (sEIOT/sEEOT) in 10, nonventilated, healthy subjects. Simultaneously, we measured the Doppler signal of the descending aorta using duplex ultrasound (Xario, Toshiba Medical Systems) and stroke volume (SV) using noninvasive pulse contour analysis (Clearsight, Edwards Lifesciences, Irvine, California). Results During sEIOT, SV, maximum velocity time integral (VTI) of the descending aorta, and common carotid fell by 25.7% ( P = .0131), 26.1% ( P < .0001), and 18.5% ( P < .0001), respectively. During sEEOT, SV, maximum VTI of the descending aorta, and common carotid rose by: 41.3% ( P = .0051), 28.3% ( P < .0001), and 41.6% ( P < .0001), respectively. There was good correlation between change in aortic VTI and carotid VTI ( r 2 = 0.79); SV and aortic VTI ( r 2 = 0.82), and SV and carotid VTI ( r 2 = 0.95).The coefficient of variation of the VTI measured by the Doppler patch was roughly 60% less than that of the duplex system. Conclusions The pattern of SV change induced by a sEIOT/sEEOT in nonmechanically ventilated volunteers is reflected in the common carotid artery and descending aorta. The VTI variability of the Doppler patch was less than that of the traditional, duplex Doppler.
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Kenny et al. (2020) conducted an observational in healthy subjects (n=10). Wearable carotid Doppler ultrasound vs. Duplex ultrasound was evaluated on Changes in stroke volume and maximum velocity time integral (VTI) (p=<0.0001). A wearable carotid Doppler tracked stroke volume changes during simulated occlusion tests, showing strong correlation with stroke volume (r2=0.95) and 60% less VTI variability than duplex ultrasound.
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