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April 14, 2010Circulation Cardiovascular Quality and OutcomesOpen Access

Quantifying the Early Health Status Benefits of Successful Chronic Total Occlusion Recanalization

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Why the study?

Does successful percutaneous coronary intervention for chronic total occlusion improve 1-month health status compared to unsuccessful recanalization in patients with CTO?

Population

125 patients undergoing percutaneous coronary intervention for coronary chronic total occlusions in the…

Comparison

Successful percutaneous coronary intervention… vs Unsuccessful percutaneous coronary intervention…

Design

Cohort

Follow-up

1 month

Authors

JGJ. Aaron GranthamInterventional CardiologyPJPhilip G. JonesCross-Cutting CardiologyLCLouis CannonUniversity of North Carolina Health Care

Discussion

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Implication

May inform shared decision-making in symptomatic CTO patients; leaves open confirmation in randomized trials.

Structured PICO

Does successful percutaneous coronary intervention for chronic total occlusion improve 1-month health status compared to unsuccessful recanalization in patients with CTO?

P
Population
125 patients undergoing percutaneous coronary intervention for coronary chronic total occlusions (CTOs) in the FACTOR trial
I
Intervention
Successful percutaneous coronary intervention for CTO recanalization
C
Comparator
Unsuccessful percutaneous coronary intervention for CTO recanalization
O
Outcome
1-month health status outcomes measured by the Seattle Angina Questionnaire (SAQ), including angina frequency, physical limitation, and quality of lifepatient reported

Successful percutaneous recanalization of chronic total occlusions provides significant early improvements in angina, physical function, and quality of life, particularly in symptomatic patients.

Cite This Study

Grantham et al. (2010) studied this question.

synapsesocial.com/papers/6a81cc1471edfdad573c8cd2https://doi.org/10.1161/circoutcomes.108.825760

Topics

Chronic total occlusion PCICoronary CT angiography
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of Life after Late Invasive Therapy for Occluded Arteries2009 · 43 citations
  2. 2A novel approach to chronic total occlusions: The crosser system2006 · 62 citations
  3. 3Disease-Specific Health Status After Stent-Assisted Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery2003 · 88 citations
  4. 4A Randomized Trial Comparing Coronary Angioplasty with Coronary Bypass Surgery1994 · 736 citations