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October 28, 2020Cardiovascular revascularization medicineOpen Access

Over Ten Years' Follow-Up of Chronic Total Coronary Occlusion Angioplasty

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Key result

Successful percutaneous coronary intervention for chronic total occlusion was associated with improved long-term survival compared with failed procedures (P=0.0147).

Why the study?

Although successful CTO-PCI has been linked to symptom relief and clinical benefits, the long-term benefit of percutaneous recanalization of CTO remains unclear.

Does successful CTO-PCI improve long-term survival in patients with chronic total occlusion compared to failed CTO-PCI?

Population

477 patients undergoing CTO-PCI

Comparison

Successful CTO-PCI vs failed CTO-PCI

Design

Observational cohort study

Follow-up

Mean 139.8 months

Authors

KYKohei YonedaTokushima Red Cross HospitalTTTakefumi TakahashiTokushima Red Cross HospitalKKKoichi KishiKyoto University

Discussion

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Implication

May support survival benefit of successful CTO-PCI; leaves open causal confirmation in randomized trials.

Study Design

Type

Cohort (n=477)

Structured PICO

Does successful CTO-PCI improve long-term survival in patients with chronic total occlusion compared to failed CTO-PCI?

P
Population
477 patients with chronic total coronary occlusion who underwent percutaneous coronary intervention, followed for a mean of 139.8 months.
E
Exposure
Successful percutaneous coronary intervention for chronic total occlusion (CTO-PCI)
C
Comparator
Unsuccessful (failed) percutaneous coronary intervention for chronic total occlusion
O
Outcome
Long-term survival at mean follow-up of 139.8 monthshard clinical

Main Result

p-value: p=0.0147

Successful CTO-PCI, particularly of the left anterior descending artery, is associated with improved long-term survival compared to failed CTO-PCI over a >10-year follow-up.

Cite This Study

Yoneda et al. (2020) conducted a cohort in Chronic total coronary occlusion (n=477). Successful CTO-PCI vs. Failed CTO-PCI was evaluated on Long-term survival (p=0.0147). Successful percutaneous coronary intervention for chronic total occlusion was associated with improved long-term survival compared with failed procedures (P=0.0147).

synapsesocial.com/papers/6a9c29c48680cd2c75851dbfhttps://doi.org/10.1016/j.carrev.2020.10.013

Topics

Percutaneous coronary interventionChronic total occlusion PCI
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Improvement in left ventricular ejection fraction and wall motion after successful recanalization of chronic coronary occlusions1998 · 228 citations
  2. 2Percutaneous Coronary Intervention in the Current Era Compared With 1985–19862000 · 319 citations
  3. 3Quantifying the Early Health Status Benefits of Successful Chronic Total Occlusion Recanalization2010 · 223 citations
  4. 4Successful revascularization improves long-term clinical outcome in patients with chronic coronary total occlusion2016 · 19 citations