Population
Rat 5/6th renal mass reduction (RMR) model
Design
Preclinical
Follow-up
1, 3 and 5 months
Authors
Loading...
Hypothesis-generating for endoglin in hypertensive renal damage; leaves open causal role and therapeutic relevance in human CKD.
In a rat model of renal mass reduction, endoglin expression is upregulated, coinciding with severe hypertension and progressive renal damage.
Rodríguez-Peña et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: