Population
Mice carrying a targeted mutation of Tbx20
Design
Preclinical
Authors
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Tbx20 mouse data remain preclinical; extends cardiac developmental models but leaves open human congenital heart disease relevance.
Tbx20 is essential for the progression from a linear heart tube to a multi-chambered heart by repressing Tbx2 in myocardial precursor cells.
Singh et al. (2005) studied this question.
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