Population
Cells infected with poliovirus (in vitro model)
Design
Preclinical
Authors
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Uncoating required for poliovirus membrane permeabilization to proteins; leaves open mechanistic role in viral entry for other picornaviruses.
The uncoating of poliovirus is required for the permeabilization of cell membranes to proteins, preventing the delivery of co-entering molecules to the cytoplasm if uncoating is hindered.
Almela et al. (1991) studied this question.
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