Why the study?
Oxidative stress plays a pivotal role in the pathogenesis of endothelial dysfunction, warranting synthesis of evidence linking reactive oxygen species imbalance to impaired endothelial function in hypertension.
Do pharmacological and non-pharmacological strategies targeting oxidative stress improve endothelial function in hypertensive states?
Design
Review
Authors
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Supports conventional agents and lifestyle for endothelial benefits in hypertension; leaves open translation of novel redox-targeted compounds.
Do pharmacological and non-pharmacological strategies targeting oxidative stress improve endothelial function in hypertensive states?
Targeting endothelial oxidative stress through existing drugs and lifestyle modifications offers potential vascular benefits in hypertension, though novel targeted therapies face translational hurdles.
Jinyan Liu (2025) studied this question.
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