May 8, 2007Heart
A propensity-matched study of the effect of diabetes on the natural history of heart failure: variations by sex and age
Why the study?
Does diabetes increase the risk of mortality and hospitalization in heart failure patients, and does this effect vary by sex and age?
Population
4,112 propensity-matched heart failure patients from the Digitalis Investigation Group trial.
Comparison
History of diabetes vs No history of diabetes (propensity score-matched)
Design
Cohort
Authors
Discussion
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Member takes
Implication
Diabetes may heighten mortality risk more in older women with HF; leaves open whether sex-age interactions require targeted study.
Structured PICO
Does diabetes increase the risk of mortality and hospitalization in heart failure patients, and does this effect vary by sex and age?
P
Population
4,112 propensity-matched heart failure patients (2,056 with diabetes and 2,056 without diabetes) from the Digitalis Investigation Group trial.
I
Intervention
History of diabetes
C
Comparator
No history of diabetes (propensity score-matched)
O
Outcome
All-cause mortalityhard clinical
Diabetes confers a greater relative risk of mortality and hospitalization in women with heart failure compared to men, an effect primarily driven by patients aged 65 and older.
Cite This Study
Ahmed et al. (2007) studied this question.