Why the study?
Does diltiazem, nitrendipine, or their combination improve blood pressure and angina symptoms in patients with moderate systemic hypertension and stable angina pectoris?
Population
48 patients with both moderate systemic hypertension and stable angina pectoris
Comparison
Diltiazem 240 mg/day, nitrendipine 20 mg/day… vs Placebo
Design
RCT, randomized, crossover, placebo-controlled
Authors
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Supports CCB selection for comorbid hypertension and stable angina; confirms comparable efficacy of diltiazem and nitrendipine in this population.
Does diltiazem, nitrendipine, or their combination improve blood pressure and angina symptoms in patients with moderate systemic hypertension and stable angina pectoris?
Diltiazem, nitrendipine, and their combination are effective therapies for simultaneously managing systemic hypertension and stable angina pectoris.
Andreyev et al. (1991) studied this question.
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