November 19, 2013PLoS ONEOpen Access

Effect of Antioxidant Supplementation on Exercise-Induced Cardiac Troponin Release in Cyclists: A Randomized Trial

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Why the study?

Does astaxanthin supplementation reduce exercise-induced cardiac troponin release in well-trained male cyclists?

Population

32 well-trained male cyclists (mean age 25±5 years, weight 73±7 kg, maximum O2 uptake 60±5 mL·kg·min, Wmax…

Comparison

Astaxanthin 20 mg/day for 4 weeks. vs Placebo for 4 weeks.

Design

RCT, randomized, double-blind

Follow-up

4 weeks

Authors

LKLieke J.J. KlinkenbergRadboud University Nijmegen GHGuido R.M.M. HaenenMaastricht University ABAalt BastGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Astaxanthin does not reduce exercise-induced troponin release in trained cyclists; challenges antioxidant cardioprotection hypotheses and does not support clinical use.

Structured PICO

Does astaxanthin supplementation reduce exercise-induced cardiac troponin release in well-trained male cyclists?

Population

32 well-trained male cyclists (mean age 25±5 years, weight 73±7 kg, maximum O2 uptake 60±5 mL·kg(-1)·min(-1), Wmax 5.4±0.5 W·kg(-1)).

Intervention

Astaxanthin 20 mg/day for 4 weeks.

Comparator

Placebo for 4 weeks.

Outcome

Exercise-induced cardiac troponin T release (measured by the incremental area under the curve).surrogate

Astaxanthin supplementation (20 mg/day for 4 weeks) does not reduce exercise-induced cardiac troponin T release or improve antioxidant capacity in well-trained male cyclists.

Cite This Study

Klinkenberg et al. (2013) studied this question.

synapsesocial.com/papers/6a824610a8461dff0846c66d https://doi.org/10.1371/journal.pone.0079280

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November 19, 2013PLoS ONEOpen Access

Effect of Antioxidant Supplementation on Exercise-Induced Cardiac Troponin Release in Cyclists: A Randomized Trial

View Full Paper

Ask AI

Bookmark

Why the study?

Does astaxanthin supplementation reduce exercise-induced cardiac troponin release in well-trained male cyclists?

Population

32 well-trained male cyclists (mean age 25±5 years, weight 73±7 kg, maximum O2 uptake 60±5 mL·kg·min, Wmax…

Comparison

Astaxanthin 20 mg/day for 4 weeks. vs Placebo for 4 weeks.

Design

RCT, randomized, double-blind

Follow-up

4 weeks

Authors

LKLieke J.J. KlinkenbergRadboud University Nijmegen GHGuido R.M.M. HaenenMaastricht University ABAalt BastGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Astaxanthin does not reduce exercise-induced troponin release in trained cyclists; challenges antioxidant cardioprotection hypotheses and does not support clinical use.

Structured PICO

Does astaxanthin supplementation reduce exercise-induced cardiac troponin release in well-trained male cyclists?

Population

32 well-trained male cyclists (mean age 25±5 years, weight 73±7 kg, maximum O2 uptake 60±5 mL·kg(-1)·min(-1), Wmax 5.4±0.5 W·kg(-1)).

Intervention

Astaxanthin 20 mg/day for 4 weeks.

Comparator

Placebo for 4 weeks.

Outcome

Exercise-induced cardiac troponin T release (measured by the incremental area under the curve).surrogate

Astaxanthin supplementation (20 mg/day for 4 weeks) does not reduce exercise-induced cardiac troponin T release or improve antioxidant capacity in well-trained male cyclists.

Cite This Study

Klinkenberg et al. (2013) studied this question.

synapsesocial.com/papers/6a824610a8461dff0846c66d https://doi.org/10.1371/journal.pone.0079280

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