February 1, 2001Obesity Research

QT Dispersion in Uncomplicated Human Obesity

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Why the study?

Does uncomplicated obesity or overweight increase QT dispersion compared to normal weight healthy controls?

Population

146 subjects including 54 obese patients, 35 overweight patients, and 57 normal weight healthy controls…

Comparison

Uncomplicated obesity and overweight vs Normal weight healthy controls

Design

Cross-sectional

Authors

AGAndrea GirolaAziende Socio Sanitaria Territoriale Rhodense RER. EnriniUniversity of Milan FGFrancesca GarbettaUniversity of Milan

Discussion

Member takes

Implication

Uncomplicated obesity or overweight was not associated with increased QT dispersion; hypothesis-generating and should not yet change clinical risk stratification.

Structured PICO

Does uncomplicated obesity or overweight increase QT dispersion compared to normal weight healthy controls?

Population

146 subjects including 54 obese patients (mean BMI 38.1 +/- 0.9 kg/m2), 35 overweight patients (mean BMI 27.3 +/- 0.2 kg/m2), and 57 normal weight healthy controls (mean BMI 21.9 +/- 0.2 kg/m2). Mean age 38.4 +/- 1.2 years. Obese and overweight patients had no heart disease, hypertension, diabetes, impaired glucose tolerance, or hormonal, hepatic, renal, or electrolyte disorders.

Intervention

Uncomplicated obesity and overweight (observational exposure)

Comparator

Normal weight healthy controls

Outcome

QT interval dispersion (QTD)surrogate

Uncomplicated obesity or overweight is not associated with increased QT dispersion compared to normal weight healthy controls.

Cite This Study

Girola et al. (2001) studied this question.

synapsesocial.com/papers/6a8248515a62cdcac13f16fd https://doi.org/10.1038/oby.2001.9

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Implication

Uncomplicated obesity or overweight was not associated with increased QT dispersion; hypothesis-generating and should not yet change clinical risk stratification.

QT Dispersion in Uncomplicated Human Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

QT Dispersion in Uncomplicated Human Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider