Why the study?
Does lacidipine reduce blood pressure more effectively and safely than amlodipine in patients with mild-to-moderate hypertension?
Does lacidipine reduce blood pressure more effectively and safely than amlodipine in patients with mild-to-moderate hypertension?
Lacidipine 4 mg daily demonstrated a significantly greater reduction in diastolic blood pressure and fewer adverse events compared to amlodipine 10 mg daily in patients with mild-to-moderate hypertension.
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Lacidipine may be preferred over amlodipine for greater diastolic BP reduction and tolerability; confirms superior efficacy in this RCT for mild-to-moderate hypertension.
Lombardo et al. (1994) studied this question.
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