Why the study?
Does H 234/09 (Almokalant) alter action potential duration and inotropy in isolated human ventricular muscle?
Does H 234/09 (Almokalant) alter action potential duration and inotropy in isolated human ventricular muscle?
Almokalant acts as a class III antiarrhythmic agent with associated positive inotropic effects in isolated human ventricular muscle.
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Does not support clinical use; leaves open translation of class III effects with positive inotropy to humans.
Carlsson et al. (1991) studied this question.
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