Why the study?
What are the independent predictors of left ventricular enlargement and hypertrophy in a middle-aged and geriatric population?
Population
1,914 middle-aged and geriatric participants from a community-based cohort, mean age 59.5 years, 32.3% male.
Design
Cross-sectional
Authors
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Supports risk stratification with BMI, central BP, and BNP in middle-aged adults; leaves open causal effects and need for prospective validation.
What are the independent predictors of left ventricular enlargement and hypertrophy in a middle-aged and geriatric population?
BMI, central blood pressure, and BNP are robust independent predictors of left ventricular remodeling in middle-aged and older adults, whereas augmentation index has limited utility.
Lezhou et al. (2012) studied this question.
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