Population
human embryonic stem cell-derived cardiomyocytes (hESC-CMs)
Comparison
Gene transfer of calsequestrin via recombinant… vs Ad-CMV-GFP and Ad-CMV-CSQDelta-IRES-GFP
Design
Preclinical
Authors
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May advance hESC-CM maturation for disease modeling; leaves open clinical translation of cell therapies.
Gene transfer of calsequestrin facilitates the maturation of calcium handling properties in human embryonic stem cell-derived cardiomyocytes, potentially improving their utility for cell-based therapies and disease modeling.
Liu et al. (2009) studied this question.
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