Population
Xenopus oocytes and biopsies from patients with malignant gliomas and nonmalignant human cortical tissues
Comparison
Expression of gBK vs hbr5 for in vitro studies; nonmalignant human…
Design
Preclinical
Authors
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gBK merits functional validation in glioma models; leaves open its utility as a therapeutic target.
A novel BK channel isoform, gBK, exhibits distinct electrophysiological properties and its overexpression correlates with malignancy grade in human gliomas.
Liu et al. (2002) studied this question.
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