Why the study?
Does bedtime administration of olmesartan 40 mg improve nocturnal blood pressure fall and albuminuria compared to morning administration in type 2 diabetic patients with newly diagnosed hypertension?
Does bedtime administration of olmesartan 40 mg improve nocturnal blood pressure fall and albuminuria compared to morning administration in type 2 diabetic patients with newly diagnosed hypertension?
Bedtime dosing of olmesartan significantly reduces nighttime systolic and mean blood pressure compared to morning dosing in diabetic hypertensive patients, promoting a dipper pattern.
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May support bedtime olmesartan for nocturnal BP control in diabetic hypertension; hypothesis-generating and requires confirmation before practice change.
Bernardo García de la Villa (2009) studied this question.
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