February 5, 2014PLoS ONEOpen Access

An Increase in Tobacco Craving Is Associated with Enhanced Medial Prefrontal Cortex Network Coupling

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Population

nicotine dependent participants

Design

Other

Follow-up

~1 hour

Authors

AJAmy C. JanesNational Institute on Drug Abuse SFStacey FarmerAlbany Stratton VA Medical Center Albany BFBlaise B. FrederickHarvard University

Discussion

Member takes

Implication

Suggests OMPFC connectivity as craving biomarker; hypothesis-generating for circuit-targeted cessation trials.

Structured PICO

Population

nicotine dependent participants

Outcome

association between subjective craving and resting state fMRI OMPFC network couplingsurrogate

Increased tobacco craving is associated with enhanced coupling between the orbital and medial prefrontal cortex network and other addiction-related brain regions.

Cite This Study

Janes et al. (2014) studied this question.

synapsesocial.com/papers/6a8290c35bcab2ccdb8d5dba https://doi.org/10.1371/journal.pone.0088228

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An Increase in Tobacco Craving Is Associated with Enhanced Medial Prefrontal Cortex Network Coupling

Discussion

Member takes

Implication

Structured PICO

Cite This Study

An Increase in Tobacco Craving Is Associated with Enhanced Medial Prefrontal Cortex Network Coupling

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider