Why the study?
Does bisoprolol compared to nitrendipine affect exercise capacity in hypertensive patients with regular physical activity?
Population
96 adults, aged 18-65 years, with mild to moderate hypertension who take regular exercise.
Comparison
Bisoprolol 10 mg daily for 12 weeks vs Nitrendipine 20 mg daily for 12 weeks
Design
RCT, randomized, double-blind
Follow-up
12 weeks
Authors
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Supports long-term bisoprolol use in active hypertensives without exercise impairment; confirms equivalence to nitrendipine and extends safety data.
Does bisoprolol compared to nitrendipine affect exercise capacity in hypertensive patients with regular physical activity?
Long-term treatment with bisoprolol does not significantly impair exercise capacity or maximal workload compared to nitrendipine in active hypertensive patients.
Brion et al. (2000) studied this question.
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