Why the study?
Does nitrendipine 20 mg once daily improve arterial rigidity and reduce blood pressure in hypertensive patients?
Population
17 hypertensive patients
Comparison
Nitrendipine 20 mg once daily for 1 month vs Placebo for 1 month
Design
RCT, double-blind
Follow-up
1 month
Authors
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Supports nitrendipine 20 mg daily for 24-hour BP control and arterial stiffness reduction in hypertension; extends CCB evidence to ambulatory and PWV endpoints.
Does nitrendipine 20 mg once daily improve arterial rigidity and reduce blood pressure in hypertensive patients?
Nitrendipine 20 mg once daily effectively lowers blood pressure and improves markers of arterial stiffness over a 24-hour period in hypertensive patients.
Asmar et al. (1992) studied this question.
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