Why the study?
Does nitrendipine 20 mg once daily reduce 24-hour blood pressure compared to nicardipine slow release 40 mg twice daily in men with mild essential hypertension?
Population
12 men (aged 39-55 years) with mild essential hypertension
Comparison
Nitrendipine 20 mg once daily for 4 weeks vs Nicardipine slow release 40 mg twice daily for 4…
Design
RCT, randomized, cross over study
Follow-up
4 weeks per active treatment
Authors
Loading...
Nicardipine slow-release twice daily may be favored for sustained 24-hour BP control in mild hypertension; extends comparative CCB dosing data from RCT.
Does nitrendipine 20 mg once daily reduce 24-hour blood pressure compared to nicardipine slow release 40 mg twice daily in men with mild essential hypertension?
In men with mild essential hypertension, nicardipine slow release twice daily provides more sustained 24-hour blood pressure reduction than nitrendipine once daily.
Fogari et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: