Why the study?
Does slow-release nicardipine reduce ambulatory and clinic blood pressure in patients with mild essential hypertension?
Population
11 patients with mild essential hypertension (mean clinic BP 173 +/- 6.6/103 +/- 1.9 mmHg)
Comparison
Nicardipine 60 mg twice daily for 4 weeks vs Matching placebo (cross-over design)
Design
RCT, randomised cross-over, double-blind, placebo-controlled
Follow-up
4 weeks
Authors
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Supports slow-release nicardipine for BP control in mild hypertension; confirms ambulatory reduction in this RCT.
Does slow-release nicardipine reduce ambulatory and clinic blood pressure in patients with mild essential hypertension?
Slow-release nicardipine 60 mg twice daily effectively reduces ambulatory and clinic blood pressure in patients with mild hypertension.
Cox et al. (1989) studied this question.
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