Why the study?
Does slow release nicardipine 50 mg twice daily reduce blood pressure in subjects with essential hypertension compared to placebo?
Population
40 subjects with essential hypertension
Comparison
Slow release nicardipine 50 mg twice daily for 3… vs Placebo
Design
RCT, randomized, double-blind
Follow-up
3 weeks
Authors
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Supports nicardipine for BP control in essential hypertension; confirms RCT efficacy independent of measurement method.
Does slow release nicardipine 50 mg twice daily reduce blood pressure in subjects with essential hypertension compared to placebo?
Slow release nicardipine 50 mg twice daily significantly reduces blood pressure in essential hypertension, though acute intravenous response does not reliably predict individual chronic efficacy.
Bellet et al. (1987) studied this question.
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