Why the study?
Does nicardipine improve forearm arterial haemodynamics in patients with mild to moderate essential hypertension?
Population
26 patients with mild to moderate essential hypertension
Design
Cohort
Follow-up
3 months (for chronic group)
Authors
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Associated with improved arterial compliance in hypertension; leaves open need for randomized outcome trials before practice change.
Does nicardipine improve forearm arterial haemodynamics in patients with mild to moderate essential hypertension?
Nicardipine lowers blood pressure through direct vasodilatory action in small and large arteries, improving peripheral blood flow and arterial compliance.
Levenson et al. (1985) studied this question.
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