Why the study?
Does nitrendipine reduce blood pressure as effectively as propranolol in hypertensive patients?
Population
23 patients (11 in nitrendipine group, 12 in propranolol group) requiring antihypertensive therapy.
Comparison
Nitrendipine administered two times daily for 14… vs Propranolol for 14 weeks following a 2-week…
Design
RCT, randomized, double-blind
Follow-up
14 weeks
Authors
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Offers clinicians a comparable alternative to propranolol; confirms 24-hour ambulatory BP equivalence in RCT.
Does nitrendipine reduce blood pressure as effectively as propranolol in hypertensive patients?
Nitrendipine administered twice daily is as effective as propranolol in reducing 24-hour ambulatory and office blood pressure.
Zachariah et al. (1987) studied this question.
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