Why the study?
Does nitrendipine improve hemodynamic and echocardiographic parameters in patients with mild to moderate essential hypertension?
Population
14 patients with mild to moderate essential hypertension
Comparison
Nitrendipine therapy for 3 months vs Pretreatment baseline
Design
Cohort
Follow-up
3 months
Authors
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Nitrendipine was associated with BP and LV mass reductions in mild hypertension; leaves open outcome benefits pending randomized trials.
Does nitrendipine improve hemodynamic and echocardiographic parameters in patients with mild to moderate essential hypertension?
Long-term nitrendipine therapy effectively lowers blood pressure and improves left ventricular mass and function in patients with essential hypertension without reflex cardiac stimulation.
Grossman et al. (1988) studied this question.
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